

💤 Sleep tight, leak-free, and fresh all night long!
Depend Night Defense Adult Diapers for Women deliver up to 12 hours of reliable overnight protection with a super absorbent core that locks away 30x its weight in moisture. Featuring OdorBlock technology and a gentle, secure fit for small waists (24–30"), these disposable underwear are perfect for incontinence, postpartum bladder leaks, and nighttime use. Available in a discreet blush color and eligible for HSA/FSA, they combine comfort, style, and advanced protection to keep you dry and confident through the night.















| ASIN | B07B2WNTT4 |
| Best Sellers Rank | #248 in Health & Household ( See Top 100 in Health & Household ) #5 in Incontinence Protective Briefs & Underwear |
| Customer Reviews | 4.5 4.5 out of 5 stars (12,006) |
| Date First Available | May 31, 2018 |
| Department | Women's |
| Is Discontinued By Manufacturer | No |
| Item model number | 00036000517019 |
| Manufacturer | Kimberly-Clark Corp. |
| Product Dimensions | 5.91 x 8.27 x 9.84 inches; 2.03 Pounds |
E**N
Comparison of Elder Incontenence Products.
Use: elder care. I'm reviewing three incontinence products, for comparison. Depend Night Defense has been excellent in terms of fit, absorption (quantity and quality), and preventing leakage, even overnight. I bought the medium (per the chart) and it fits great; plenty of stretch. The absorption easily handled two 'wee's and/or one wee and a poo (I'm being delicate here, play along please!) with NO leakage! There is no smell to the product, so it is discreet. I have not noticed any skin irritation. Five stars, no complaints. Always Discreet Boutique is excellent in terms of absorption and preventing leakage (daytime use). However, I would recommend sizing up, as the Medium is smaller than the Depend Medium, above. They easily handle either one 'wee' and/or 'poo' with no leakage. They do have a "feminine product" scent, though it is not overpowering. For a couple hours, you will catch whiffs of this distinctive scent. No skin irritation that I've noticed. Four stars (would be five stars, but for the fit). Tena Stylish "Super Plus Heavy" was a disappointment in comparison. I bought Large instead of Medium, as recommended by many reviewers. The width/waist was good, but they fit more like hipsters than briefs. The back coverage was insufficient, and they leaked through to the seat of the pants, even though I did not use it for bedtime/laying prone. Since I had to change them out about two hours after putting them on, I can't speak to skin irritation. They do not have any scent. Two stars.
A**A
Good for Grandma
I purchased the Depend Night Defense Overnight Underwear for my 96-year-old grandmother, and they’ve truly been a game changer for her comfort and health. We use them every night and also on days when she’s not feeling well enough to get around easily. The fit is secure but gentle, with soft material that doesn’t irritate her skin. Most importantly, they keep her clean, dry, and protected through the night, which has greatly reduced the risk of UTIs, something we struggled with before switching to these. The overnight absorbency is excellent. Even after hours of wear, there’s no leaking, no odor, and she still feels fresh in the morning. The blush color is also a nice touch, it feels a bit more dignified than plain white. We’ve tried other brands, but these stand out for their combination of comfort, absorbency, and skin health. For caregivers, knowing your loved one is protected and comfortable brings incredible peace of mind. Highly recommend for anyone caring for an elderly family member or someone recovering from childbirth who needs reliable overnight protection.
E**S
Reliable Overnight Protection with a Comfortable Fit
Reliable Overnight Protection with a Comfortable Fit Depend Night Defense Underwear for Women is one of the most dependable (no pun intended) overnight protection options available. I first purchased these for a family member recovering from surgery, and they’ve since become the go-to for comfort, confidence, and dryness through the night. The material is impressively soft—closer to real fabric than the crinkly texture found in many disposable briefs. The blush color and feminine cut make them feel less clinical, and the fit is snug without being tight. They pull on easily, stay in place even when turning in bed, and don’t bunch or sag after several hours. Performance-wise, they hold up remarkably well. The absorbent core locks in moisture fast, and odor control is effective even after a full night’s use. There’s no noticeable leakage, and the waistband keeps everything comfortably secure. They’re also quiet under clothing, making them discreet enough for day use if needed. A tip: for best results, pick the right size based on both waist and hip measurements—fit makes a big difference in comfort and leak protection. Bottom line: soft, secure, and genuinely protective overnight underwear that delivers comfort and dignity. A top choice for dependable nighttime protection or post-surgery recovery.
K**M
Did the job and are comfy!
I usually get the Always brand in the same size (L) but tried these out this time. They're more comfortable than the Always brand bc they aren't tight around my thighs and hips. Because I'm not constantly pulling or adjusting, they're more durable, in my opinion. I'm using them along with my June cup for added protection and they seem pretty absorbent when necessary. I thought the light color would be weird, but all is well so far. I'll definitely keep these in my monthly arsenal! (For reference, I usually wear a size 14-16 in pants)
W**W
Life Changing
Life changing! the quality is excellent. It is very absorbent and holds a lot. It is SO great for travelling long distances. The Fit is great and takes the worry away.
A**R
Practical Solution for Overnight Protection
The Depend Night Defense Adult Incontinence & Postpartum Bladder Leak Underwear for Women, Disposable, Overnight, Medium, Blush, 60 Count (4 Packs of 15), Packaging May Vary was properly packaged and delivered safely the next day. This product offers a reliable solution for those seeking overnight protection from bladder leaks. With a medium size designed specifically for comfort, the underwear features a soft, discreet fit that allows for natural movement. It is disposable, which adds convenience for overnight use. Each pack contains 15 pairs, providing ample supply for multiple nights. The absorbent core is designed to handle overnight incidents, giving users peace of mind during sleep. The blush color adds a touch of understated style, making it a more appealing option compared to traditional incontinence products. Overall, this product combines functionality and comfort, making it a practical choice for women needing extra support during the night.
L**G
It’s a terrible product which only lasts a day if that! The crotch is fine but the panty part shreds after just a few uses of going to the bathroom 🚽! It literally falls apart so don’t waste your money! Don’t buy! So disappointed ☹️! I’m glad it’s not the first Depend product that I have used otherwise I would never buy Depend products at all! Regular Depends are ok!
A**G
Cumplen du objetivo y son cómodos, solo que el precio varía de un mes a otro y se puede encontrar mas barato en tiendas de autoservicio y farmacias.
B**H
I have purchased this product in the store previously...so, I know that we would be happy with it. With the pandemic, I have been ordering everything online that has been possible. Product arrived in a few days.
A**Y
SSo absorbant
J**N
Great fit
Trustpilot
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