







💤 Sleep tight, leak-free, and confident all night long!
Depend Night Defense Adult Diapers for Women offer up to 12 hours of reliable overnight protection with a super absorbent core that locks in 30x its weight in moisture. Featuring OdorBlock technology and a soft, feminine blush design, these disposable underwear provide discreet comfort and dryness for incontinence and postpartum bladder leaks. Available in multiple sizes and HSA/FSA eligible, they combine advanced performance with everyday practicality.
















| ASIN | B0CGF9KYS4 |
| Age Range Description | Adult |
| Best Sellers Rank | #302 in Health & Household ( See Top 100 in Health & Household ) #6 in Incontinence Protective Briefs & Underwear |
| Brand Name | Depend |
| Color | Blush |
| Customer Reviews | 4.5 out of 5 stars 11,999 Reviews |
| Global Trade Identification Number | 00036000555974 |
| Incontinence Protector Size | Medium |
| Incontinence Protector Type | Adult Incontinence Underwear |
| Item Dimensions | 5.7 x 8.34 x 16.34 inches |
| Item Height | 16.34 inches |
| Item Length | 5.7 Inches |
| Lining Description | Ultra-soft fabric |
| Manufacturer | Kimberly-Clark Corp. |
| Material Type | Polypropylene |
| Material Type Free | Latex Free |
| Number of Items | 1 |
| Package Type Name | Urine Protection |
| Pattern | No |
| Recommended Uses For Product | Adult Diapers |
| Reusability | Disposable |
| Size | Medium |
| Target Audience | Unisex-Adults, Women |
| UPC | 036000555974 |
| Unit Count | 24 Count |
| Water Resistance Level | Not Water Resistant |
| Weight Range | 120-180 lbs |
E**S
Reliable Overnight Protection with a Comfortable Fit
Reliable Overnight Protection with a Comfortable Fit Depend Night Defense Underwear for Women is one of the most dependable (no pun intended) overnight protection options available. I first purchased these for a family member recovering from surgery, and they’ve since become the go-to for comfort, confidence, and dryness through the night. The material is impressively soft—closer to real fabric than the crinkly texture found in many disposable briefs. The blush color and feminine cut make them feel less clinical, and the fit is snug without being tight. They pull on easily, stay in place even when turning in bed, and don’t bunch or sag after several hours. Performance-wise, they hold up remarkably well. The absorbent core locks in moisture fast, and odor control is effective even after a full night’s use. There’s no noticeable leakage, and the waistband keeps everything comfortably secure. They’re also quiet under clothing, making them discreet enough for day use if needed. A tip: for best results, pick the right size based on both waist and hip measurements—fit makes a big difference in comfort and leak protection. Bottom line: soft, secure, and genuinely protective overnight underwear that delivers comfort and dignity. A top choice for dependable nighttime protection or post-surgery recovery.
A**A
Good for Grandma
I purchased the Depend Night Defense Overnight Underwear for my 96-year-old grandmother, and they’ve truly been a game changer for her comfort and health. We use them every night and also on days when she’s not feeling well enough to get around easily. The fit is secure but gentle, with soft material that doesn’t irritate her skin. Most importantly, they keep her clean, dry, and protected through the night, which has greatly reduced the risk of UTIs, something we struggled with before switching to these. The overnight absorbency is excellent. Even after hours of wear, there’s no leaking, no odor, and she still feels fresh in the morning. The blush color is also a nice touch, it feels a bit more dignified than plain white. We’ve tried other brands, but these stand out for their combination of comfort, absorbency, and skin health. For caregivers, knowing your loved one is protected and comfortable brings incredible peace of mind. Highly recommend for anyone caring for an elderly family member or someone recovering from childbirth who needs reliable overnight protection.
W**W
Life Changing
Life changing! the quality is excellent. It is very absorbent and holds a lot. It is SO great for travelling long distances. The Fit is great and takes the worry away.
K**M
Did the job and are comfy!
I usually get the Always brand in the same size (L) but tried these out this time. They're more comfortable than the Always brand bc they aren't tight around my thighs and hips. Because I'm not constantly pulling or adjusting, they're more durable, in my opinion. I'm using them along with my June cup for added protection and they seem pretty absorbent when necessary. I thought the light color would be weird, but all is well so far. I'll definitely keep these in my monthly arsenal! (For reference, I usually wear a size 14-16 in pants)
M**Y
Truly Reliable Overnight Protection That Finally Works
After trying many brands for my mom, Depend Night Defense is the only one that’s consistently leak proof. She can wear them all night without any discomfort or problems, and they fit her perfectly. It’s such a relief to wake up with dry bedding every morning and know she can rest comfortably. The fabric is soft, not bulky, and holds up really well even on long nights. The only small drawback is that it took us a little while to realize the printed floral design goes in the front. Most other brands have markings or prints on the back, so that was confusing at first. Once we figured that out, everything’s been great. Highly recommend these for anyone who needs dependable overnight protection.
M**N
Depenable
What I like about Depends is they go up a little higher to waist. Padding is good also. They don't rip when putting them on my Mother. Cost is .30cents more each then walmarts or Mckesson but Depends quality is better.
V**R
They really work!
These Night Defense Adult Diapers are just as advertised. They are thick, absorbent and comfortable. There is no bulk nor bulge when wearing them. You can sleep easily at night knowing Depend is doing its job.
J**S
Not leak free for periods
My wife wanted to try these and she wore these on her periods at night for two days. They leaked both nights, so she is switching back to the brand she was getting before, Liv Dry, because they never leak.
Trustpilot
2 weeks ago
3 weeks ago