---
product_id: 4525860
title: "Advantage II XL Dog Vet-Recommended Flea Treatment & Prevention | Dogs Over 55 lbs. | 6-Month Supply"
brand: "advantage"
price: "982 kr"
currency: DKK
in_stock: true
reviews_count: 4
category: "Advantage"
url: https://www.desertcart.dk/products/4525860-advantage-ii-xl-dog-vet-recommended-flea-treatment-and-prevention
store_origin: DK
region: Denmark
---

# For dogs 55+ lbs Waterproof after 24 hrs Kills fleas in 12 hrs Advantage II XL Dog Vet-Recommended Flea Treatment & Prevention | Dogs Over 55 lbs. | 6-Month Supply

**Brand:** advantage
**Price:** 982 kr
**Availability:** ✅ In Stock

## Summary

> 🐾 Stay ahead of fleas—because your big dog deserves big protection!

## Quick Answers

- **What is this?** Advantage II XL Dog Vet-Recommended Flea Treatment & Prevention | Dogs Over 55 lbs. | 6-Month Supply by advantage
- **How much does it cost?** 982 kr with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.dk](https://www.desertcart.dk/products/4525860-advantage-ii-xl-dog-vet-recommended-flea-treatment-and-prevention)

## Best For

- advantage enthusiasts

## Why This Product

- Trusted advantage brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Rapid Action Formula:** Eliminates adult fleas, larvae, and eggs within 12 hours for immediate relief and ongoing protection.
- • **Month-Long Protection:** One easy topical application keeps fleas at bay for a full 30 days—no daily hassle required.
- • **Effortless Application:** Quick, no-prescription topical drops that are fragrance-free and waterproof after 24 hours—perfect for active dogs.
- • **Cost-Effective Flea Control:** Available in convenient 6-packs with subscription options to never miss a treatment and save money.
- • **Vet-Recommended Flea Defense:** Trusted by professionals for dogs over 55 lbs, ensuring your large companion stays protected.

## Overview

Advantage II Extra Large Dog is a vet-recommended, topical flea treatment designed for dogs over 55 lbs and at least 7 weeks old. It kills fleas at all life stages within 12 hours and provides 30 days of waterproof, fragrance-free protection. Easy to apply without a prescription, it breaks the flea life cycle to prevent infestations and supports your dog's health and comfort month after month.

## Description

Advantage II Extra Large Dog is the vet-recommended prevention and treatment of flea and lice infestations in dogs. Advantage II Extra Large Dog flea treatment and prevention kills adult fleas, flea larvae and flea eggs to deliver total flea protection to your dog or puppy. In fact, within 12 hours of application, Advantage II Extra Large Dog topical treatment gets straight to work killing fleas through contact, so they don’t have to bite your dog to die.This 30-day treatment effectively breaks the flea life cycle, controlling existing flea and lice infestations and preventing further infestations all month long. Fleas not only cause discomfort; they can also pose other health risks. Monthly use of Advantage II Extra Large Dog is important to protect your dog against fleas that may cause transmission of tapeworms in dogs, Flea Allergy Dermatitis and flea bite anemia.That’s why Advantage II topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that Advantage II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. Advantage II Extra Large Dog flea and lice protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use Advantage II Extra Large Dog.For the ultimate convenience in care, Advantage II Extra Large Dog is available over the counter – no prescription needed. And, you can stock up with a subscription for regular doorstep deliveries so you never miss a monthly treatment. Once Advantage II Extra Large Dog is applied, your dog is ready to get right back to exploring his favorite places – from the backyard to the dog park.Advantage II Extra Large Dog is a trademark of Elanco or its affiliates.

Review: A Helpful Tool In Our Flea Control Regimen! - We have double coated, long haired, very furry large Northern Breed Mixed Dogs. Unfortunately, fleas are a year round problem here in the San Francisco Bay Area where we live ... Ugh! Advantage II Topical Flea Treatment & Prevention is an effective tool in our flea control regimen. - Easy to apply the topical drops on your dog's skin along the backbone. - Our dogs have never had any skin irritation or other negative reactions with this product. - The 6 pack is a terrific value. I highly recommend this product.
Review: Gets the job done - It's hard to find an affordable, OTC flea repellant that applies monthly on the neck and WORKS. This stuff does the job. I have two 25 pound dogs and the small dog application is way smaller and ridiculously expensive. Our monthly budget is super tight, but I must take care of my animals, so I went looking for a cheaper way to get a good OTC flea repellant that works. This WORKS. For me. I can't guarantee it'll work for you, of course. I don't know you, I don't know your dog. Duh. Fleas are different all over the nation and some have developed immunity to this kind of repellant and some repellants just don't work. Disclaimer: I'm about to tell you what I do with this. If you decide to do the same, I take no responsibility for your results. I'm just saying this works for me. Ok, so I did some research on The Innernetz. I found out that if you get the extra large dog size, you get way more medicine for your money. It makes it cost way less per ml. I got this item. I got a little, airtight, really secure glass bottle, and a 1.0ml syringe. All from desertcart. The research I found said to use 1.2ml for a 25 pound dog. So at the beginning of every month, I open one extra large dog application, squirt it into the little glass jar, stick in the blunt syringe, and pull the plunger all the way, which is about 1.2ml. I then apply it on my dogs just as I would the small dog application. No fleas in our house. Thank GOD. Because once they get in, they're almost impossible to get rid of, and it's crazy-making. BTW, dusting diatomaceous earth and using an insect growth regulator are a good way to get rid of an infestation.

## Features

- Vet recommended flea treatment and prevention for dogs at weighing over 55 lbs., at least 7 weeks of age
- Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment
- Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days
- Easy-to-apply topical treatment, no prescription needed
- Fragrance-free formula, waterproof after 24 hours

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B004QRJJF0 |
| ASIN  | B004QRJJF0 |
| Age Range Description | 7 weeks and older |
| Best Sellers Rank | #6,179 in Pet Supplies ( See Top 100 in Pet Supplies ) #25 in Dog Flea Drops |
| Brand Name | Advantage |
| Breed Recommendation | Extra Large |
| Care Instructions | Topical Treatment |
| Color | Blacks & Grays |
| Country of Origin | United States |
| Customer Reviews | 4.5 4.5 out of 5 stars (6,667) |
| Date First Available | March 5, 2011 |
| Date First Available  | March 5, 2011 |
| Department | Flea & Tick |
| Department  | Flea & Tick |
| Directions | Application Instructions: 1. Use only on dogs. 2. Hold applicator tube in an upright position. Pull cap off tube. 3. Turn the cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. 4. Apply the entire contents of the tube evenly to three or four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until… |
| Is Discontinued By Manufacturer  | No |
| Item Dimensions LxWxH | 1.38 x 4.38 x 6.63 inches |
| Item Package Dimensions L x W x H | 6.61 x 4.33 x 1.42 inches |
| Item Weight | 0.16 Pounds |
| Item model number | 86336669 |
| Item model number  | 86336669 |
| Manufacturer | Elanco US Inc |
| Manufacturer  | Elanco US Inc |
| Model Name | Advantage II |
| Number of Items | 6 |
| Product Dimensions  | 1.38 x 4.38 x 6.63 inches; 2.56 ounces |
| Size | 6-Pack |
| Specific Uses for Product | Parasites |
| Style | XL Dog only |
| Target Audience Keyword | Dogs |

## Product Details

- **Active Ingredients:** Imidacloprid, Pyriproxyfen
- **Age Range (Description):** 7 weeks and older
- **Allergen Information:** Allergen-Free
- **Brand:** Advantage
- **Dog Breed Size:** Large
- **Item Form:** Topical
- **Item Volume:** 24 Milliliters
- **Item Weight:** 0.16 Pounds
- **Scent:** Unscented
- **UPC:** 724089203212

## Images

![Advantage II XL Dog Vet-Recommended Flea Treatment & Prevention | Dogs Over 55 lbs. | 6-Month Supply - Image 1](https://m.media-amazon.com/images/I/71cdP9dVcqL.jpg)

## Questions & Answers

**Q: I have always used Advantage on dogs AND cats.  Advantage II now says not to use on cats.  Anybody know what changed?**
A: Be a bit weary of "they have the same ingredients"  argument,  yes they do have the same percentage of ingredients but those ingredients may not be mixed homogeneously, meaning if you divvy it up you may get a larger percentage of ingredient over another.  

When you use the appropriate sized cat/dog vial all of what's in that vial gets put on your pet, so 9% of one ingredient, 1% of another 90% of "other" each and every time in the correct proportions, if for whatever reason the stuff is layered in the tube and you use a syringe to pull out 1/10th you could get 0% to 90% by volume of that ingredient that is "9%" depending upon how well mixed up it is, and Bayer really has no need to mix things up since they are packaging a product intended to use all of it in one shot.    

So if you use the dog version on cats do try to mix up the stuff in some way, shake the tube, pour it into a smaller container and mix, etc, which in itself is no guarantee things will be mixed evenly, but it's better than nothing.

**Q: can you still bathe your dog after using?**
A: My vets told me I was told not to bathe 2 days before and after. I had bathed my dog the same day, and though he was totally dry before application, He had no flea control at all a a result.  .

**Q: How many ml difference in amount for each of the sizes? like, how much per tube. for 10lb and under, large dog, extra large dog etc.**
A: Apparently the amount used on a dog doesn't matter much.   I took a new dog to the vet for shots and he applied Advantix II without my knowing it,  I said "I had just put it on him"   and he said "it doesn't matter, it won't hurt him"  and it didn't.

**Q: Is this for ticks too?**
A: No. You will want to purchase K9 Advantix. That will kill fleas and ticks.

## Customer Reviews

### ⭐⭐⭐⭐⭐ A Helpful Tool In Our Flea Control Regimen!
*by M***S on January 3, 2026*

We have double coated, long haired, very furry large Northern Breed Mixed Dogs. Unfortunately, fleas are a year round problem here in the San Francisco Bay Area where we live ... Ugh! Advantage II Topical Flea Treatment & Prevention is an effective tool in our flea control regimen. - Easy to apply the topical drops on your dog's skin along the backbone. - Our dogs have never had any skin irritation or other negative reactions with this product. - The 6 pack is a terrific value. I highly recommend this product.

### ⭐⭐⭐⭐⭐ Gets the job done
*by D***Y on August 1, 2017*

It's hard to find an affordable, OTC flea repellant that applies monthly on the neck and WORKS. This stuff does the job. I have two 25 pound dogs and the small dog application is way smaller and ridiculously expensive. Our monthly budget is super tight, but I must take care of my animals, so I went looking for a cheaper way to get a good OTC flea repellant that works. This WORKS. For me. I can't guarantee it'll work for you, of course. I don't know you, I don't know your dog. Duh. Fleas are different all over the nation and some have developed immunity to this kind of repellant and some repellants just don't work. Disclaimer: I'm about to tell you what I do with this. If you decide to do the same, I take no responsibility for your results. I'm just saying this works for me. Ok, so I did some research on The Innernetz. I found out that if you get the extra large dog size, you get way more medicine for your money. It makes it cost way less per ml. I got this item. I got a little, airtight, really secure glass bottle, and a 1.0ml syringe. All from Amazon. The research I found said to use 1.2ml for a 25 pound dog. So at the beginning of every month, I open one extra large dog application, squirt it into the little glass jar, stick in the blunt syringe, and pull the plunger all the way, which is about 1.2ml. I then apply it on my dogs just as I would the small dog application. No fleas in our house. Thank GOD. Because once they get in, they're almost impossible to get rid of, and it's crazy-making. BTW, dusting diatomaceous earth and using an insect growth regulator are a good way to get rid of an infestation.

### ⭐⭐⭐⭐⭐ Works the 1st time! Even on ferrets
*by C***A on October 13, 2023*

This is the ONLY brand I trust and will ever purchase. The formula is effective pretty quickly. My animals can't stand when I apply this to them but it is the only brand that I have found to ever kill and get rid of fleas completely, I've tried so many too! I use this on my ferrets too, but super carefully! I drip the formula into a glass vile and use a mL syringe. I've adopted many ferrets infested with fleas and this is the only formula that has ever successfully killed the fleas. It doesn't burn them, but they must be separated until it's completely dry or else they may get it in there mouths from playing with each other. Overall great product and a must-have in my home!

## Frequently Bought Together

- Advantage II XL Dog Vet-Recommended Flea Treatment & Prevention | Dogs Over 55 lbs. | 6-Month Supply
- Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 6-Month Supply
- Advantage II Small Cat Vet-Recommended Flea Treatment & Prevention | Cats 5-9 lbs. | 6-Month Supply

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*Product available on Desertcart Denmark*
*Store origin: DK*
*Last updated: 2026-01-29*