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🐾 Clear ears, happy pets—because they deserve the best care!
Zymox Advanced Formula Otic Plus is a 1.25oz enzymatic ear solution for dogs and cats that combines the LP3 Enzyme System with 1% Hydrocortisone to effectively clear biofilms, soothe itching, and reduce redness. Safe for all life stages, it requires no pre-cleaning and offers a natural, vet-trusted alternative for managing mild ear irritations.






































| Customer Reviews | 4.7 out of 5 stars 14,294 Reviews |
E**K
"Visible results from the first use, recommended"
I bought Zymox Plus for my dog after I had a strong irritation in my ears caused by a talc I used previously to clean and remove hairs from the ear canal. That product caused a pretty strong reaction, with inflammation, redness and secretion, which worried me a lot. I decided to try Zymox Plus and, from the first use, I noticed an improvement. The inflammation has been going down, the redness has decreased and my dog looks much more comfortable and calm. I have also noticed less discomfort and improvement in ear cleaning. In my personal experience, it has been a very useful product to help in the recovery and relief of the discomfort of my pet. I recommend it for similar cases, always observing the evolution of the animal and consulting the veterinarian if necessary.
R**L
Works very well!
This stuff worked wonders for my dog’s ears. I saw a review about it turning a dog’s ears red. So I read the instructions very carefully & it clearly states on the bottle if your dog is allergic to the ingredients not to use it. I was unsure if my dog was or not, so i decided to buy it & do a patch test first. Because she was excessively digging at her ears & scratching them. So when I receive the product, I did examine her ears quite well to make sure she had no open sores in them. Since she didn’t have any open sources on them . I Then did a patch test on the inside tip of her ear & waited 24 hours, to make sure she was not allergic to it. Then I proceeded as the instructions said within the first three days her ears cleared up. And they were no longer black inside & she stopped itching. It saved me a trip to the vet that’s for sure. Highly recommend this. This product hasNo smell that i noticed. It is pretty thick & clear looking so it makes it easy to apply how much you’re putting on the dog ear.
K**I
This stuff works FAST
This is the best stuff ive found! My boston has broken/floppy ears & has been having the worst flair up for the past 6 months. Weve been trying just about everything. First application & the redness is gone. The itch was almost immediately gone. My boy hasnt slept like that in months.... thank you so much to all of the other reviewers for convincing me this would work & the company for making such a great product. Worth every penny. On his second application today & he gladly came to me where he usually fights ear treatments. Couldnt be happier.
A**R
Cleared Up My Dog’s Ear Flare-Up Fast
My dog occasionally gets ear irritation — shaking his head, scratching, and redness inside the ear. It’s stressful to watch, and I always want to address it quickly before it turns into something worse. This Zymox Otic Plus has been a lifesaver for us. What I like is that it contains 1% hydrocortisone, which helps calm inflammation and itching. Within a couple of days, I noticed he wasn’t shaking his head as much, and the redness started to look better. It seems to soothe pretty quickly. The dropper tip makes it easy to apply, and I gently massage the base of the ear as directed. It’s simple to use and doesn’t require pre-cleaning, which makes the process much less stressful for both of us. Of course, for severe or recurring infections I would still consult a vet, but for mild flare-ups and irritation, this has worked really well in our experience. If your dog or cat deals with occasional ear redness or itching, this is definitely worth having in your pet care kit. It’s effective, easy to apply, and brought noticeable relief within a few days.
C**N
Works as described I concur with the other reviewers
I think it's a good product and helped my dogs ear after first couple of treatments.
A**N
Amazing !!
Works amazing! The only thing that clears up my dogs ear!!
T**.
Lifesaver!!
Absolutely phenomenal stuff!!! I'm SO thankful I came across this product, it has saved my poor cat from a very stubborn ear infection that was causing him quite some distress. Even better, I saved hundreds in a vet visit and having to put my cat through the wringer even further. Being a rescue, he HATES going in cat carriers. He gets violent, needs to be sedated, and inevitably soils himself every time. I didn't want to put him (or myself) through that if I could avoid it. I thankfully came across this! His ear was very itchy, red, and irritated. After starting Zymox, I saw notable improvement within a day of use, with significantly reduced redness and crusty discharge! Now on day 6, his ear is almost completely back to normal! No redness, very minimal crust left. I am following the instructions and will be using the product for a full 7 days. Although he only needs one more dose, I think I will give him an extra day or two just to be sure. The product itself is very goopy and sticky, which has helped reduce mess given most of it stays put in his ear where it should be. No bad odor either! I also really like not having to pre-clean my poor boy's ear, he's already not thrilled as it is. Although a bit more expensive than other ear solutions and a smaller bottle, this one is well worth the cost. I super recommend this as a last resort at home before dropping the Big $$$ and tons of stress at the vet!
B**M
Works!
Resolved completely, I hope the issue doesn't return but so far so good!!! It's been a week and his ears still look clean. I want to start by saying I didn't know what was wrong with my babies ears. I have a 6 month old kitten I adopted that had very dark waxy and dirty ears. I suspected yeast or mites. I treated for 8 days although the issue looked fully resolved on day 6. Afterwards I cleaned his ears one last time with Veterinary formula ear cleaner also sold on Amazon. He was not scratching his ears excessively but I checked his ears anyway and noticed how dirty they were and I'm shocked he wasn't scratching because they were filthy and so waxy and wet/ yeasty looking. Cats have clean ears naturally so I knew it wasn't normal. The kitten was tolerating treatment surprisingly well especially for the Zymox plus because it's a little thicker. The ear cleaner I used once after completing the Zymox he didn't like near as much but it's quite runny. His ears are really clean. In case there's an issue with mites, I plan on using on and off for a month with skipping a week between each treatment since eggs can hatch after a week or two. The vet said this would be safe to use for a month but if the issue returns I'll take my kitten to the vet. So far so good. I can't believe the amount of wax expelled from his ears.. I would purchase again.
J**S
Great product. Solved my dog’s ear problem quickly.
Wow! My dog had what I interpreted as excessive wax build up in his ear. He’s a feisty little guy and I could not get on top of it with mere cleaning and hair trimming. With a yeasty smell I turned to this product. The debris that came out of his ear was phenomenal, and now he is irritation free with a very clean ear canal. This product is highly recommended.
A**R
Cures ear infections at a low price
I haven’t had to go to the vet and pay hundreds of dollars for things to fix her ear infections since we got this stuff. I have a Chinese shar pei so it’s really common for them to get ear infections. This stuff is thick and doesn’t go everywhere, travels thru their ear and then you just wipe the excess. It’s great!
J**I
Excellent
Excellent product as describe
G**S
great product , great service
great product , seems to be working fine
B**Y
Cat yeasty ears
Had tried numerous different ways & products to rectify my cat’s yeasty ears which was giving her great irritation. Came across Zymox as a suggestion, applied once a day for 7 days- Problem solved immediately after one weeks use.! Even now a few weeks later she is irritation free and her ears are clear of black debris. Highly recommended.
Trustpilot
3 weeks ago
1 day ago