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💡 Unlock your brain’s master hormone for sharper focus and balanced vitality!
BioMatrix Pregnenolone is a micronized sublingual liquid supplement delivering 3X better absorption than capsules. It supports hormone balance by acting as the precursor to key steroid hormones, enhances cognitive function by crossing the blood-brain barrier, and promotes stress resilience through HPA axis support. Its precise drop dosing and clean formula make it ideal for personalized hormone optimization and brain health.















| ASIN | B00U36X98Q |
| Age Range Description | Adult |
| Allergen Information | Soy Free |
| Best Sellers Rank | #54,251 in Health & Household ( See Top 100 in Health & Household ) #2,084 in Blended Vitamin & Mineral Supplements |
| Brand | BioMatrix |
| Brand Name | BioMatrix |
| Container Type | Bottle |
| Customer Reviews | 4.2 out of 5 stars 1,046 Reviews |
| Dosage Form | Liquid |
| Flavor | Unflavored |
| Item Dimensions | 1.97 x 1.97 x 4.92 inches |
| Item Form | Liquid |
| Item Weight | 2.88 ounces |
| Manufacturer | BioMatrix |
| Manufacturer Part Number | 507-01 |
| Number of Items | 1 |
| Primary Supplement Type | Pregnenolone |
| Product Benefits | Hormone Balance |
| Recommended Uses For Product | Hormone Balance,Brain Health |
| Total Servings Per Container | 500 |
| UPC | 858860004078 |
| Unit Count | 1 Fluid Ounces |
J**N
Amazing-This really works 🤩 Thank you Biomatrix. ♥️ its products.
Age 73 on HRT estradiol patch, would love to keep my bones healthy, but started holding water from patch & progesterone wasn’t helping. No I wasn’t eating excessive salt either. I eat healthy & low carb, exercise regularly w much walking w golf & gym. Reduced estradiol patch to 1/2 still no relief. Pulled off patch completely-still holding water. I noticed the Pregnenolone I had in refrig. Looked up info & started taking 3 drops 2x’s today. Water started pouring out of me regularly all day (WOW). I wasn’t consuming additional water excessively. The white patches that were on my thighs when I’d press my hand (and release) are not there now—that’s fast. I understand it’s like the mother of all hormones & helps to regulate them all. I’ll continue to take this but in a lesser amount after tomorrow. Amazed at the fast results. Love Biomatrix products. Feel so relaxed & even fell asleep during a meditation this afternoon. Excited to see how my sleep is tonight. So very grateful.
M**T
Amazing.
I bought this to attempt to get off BHRT and it's working! I am truly amazed. I've only been taking for one week- worked up from one drop, to two and now three per day. Stopped taking the BHRT a couple days ago. I thought that I'd be on these three cream hormones indefinitely, which is not cheap, but it seems that this is doing as it is supposed to.. getting my body to make it's own hormones again. I'm really amazed. I don't feel any strongly noticeable effects on my memory... though at a party last night I did remember every single persons name without hesitation, so that may be an effect of it. I also feel more happy and motivated, but that might just be from the success of getting my body to work correctly again. The first clear sign that this was working was that hair was growing more normally again.. my eyebrows have filled back in, I need to shave my legs more often. (The upside of rock-bottom testosterone was body hair becoming quite sparce). I am 47 and have been on BHRT for 7 years, so this prodoct is pretty close to a miracle for me. So glad I read Suzanne Sommers book and stumbled on the section on Pregnenolone! (That book is surprisingly well written). The week before I read about preg, I tried DHEA.. and immediately broke out like a teenager! I do think that this may be giving me energy at night.. so I can't sleep.. so I may have to take once only just at breakfast. For now I'm gonna try taking at breakfast and lunch. I highly recommend this product and truly stand in amazement. Such a simple remedy! I hope other women wanting to get off HRT will try it. Good luck!
J**N
Great solution
I love that there's a sublingual formula available, 1 ingredient and a quality solution for the menopause struggles I've had getting HRT through conventional doctors. I personally enjoy the taste, it feels like it instantly absorbs and begins working. Just 2 drops makes this little bottle a great value and convenient to bring with me in my purse. Seems I am already sleeping better too.
S**Y
Helps calm me before bed
I am all over the place with this stuff after using it consistently for a month. I've had various hormone and egg reserve tests, etc., run over the years because my symptoms since my 20's have felt hormone related. All seem to test pretty normal, except I tend to have slightly low progesterone. Ok, fine, but as of late, I've been having a lot of issues sleeping even after working on my cortisol levels with an ND. I've tried supplementing with progesterone and it sort of helps, but sort of doesn't and can also make me feel wired. I've tried prescription pills, creams, and sublingual. I continue to have my hormone levels checked about ever 2 years and am also surprised the tests aren't really showing anything. Then I came across an article on pregnenolone being a precursor/ master hormone and figured I'd give it a try. I have noticed positive effects with sleeping a bit better at night, but it's a very fine balance. I do best on 2 - 3 drops. More helps me fall asleep easier, but then I wake up around 3 or 4am feeling wired. It might be one of those things where you need to gradually step up, but I have a feeling with how sensitive to hormones I am, I will probably just always remain at a lower dose, and that's ok because the positive effects even at a low dose are totally worth it. As far the nitty gritty, the dropper is pretty easy. Make sure you shake up really well and drop right away because it begins separating almost immediately. The taste is like rubbing alcohol, so not my favorite. It burns so I find I need to swirl it around my mouth quite a bit to cut it down, and then let is sit under my tongue for a couple of minutes. If I put it under there right away, it's way too strong and burns, but I've always had a more sensitive mouth and skin. I've mainly noticed improvement of sleep, but I do take 1 - 2 drops every morning and find it doesn't cause drowsiness, which is great. I'm not sure if it helps energy levels, but it certainly doesn't hurt them, for me at least.
L**E
BE VERY CAREFUL ~ NO EXPLAINATION on how to take this very powerful steroid.
The seller has sent me a second email within one week asking me to review the product. I responded to the first email by saying that I was going to wait one month before leaving a review, but I guess they do not read their customer emails. Which puts into perspective what this seller really cares about , selling their products and not about the customer. I bought this product for hormonal balance. I am 39 years old and have experienced PMS symptoms, irritation being my most severe for 2 weeks out of every month since having my first child in 2006. I was hoping that this product would relieve me, but it actually increased my aggravation and irritation. The product came very quickly, but with no instructions except for take two drops two times a day, so I watched several YouTube videos and did some reading on pregnenolone in order to understand the product and know how to take it. I didn't know whether to take it during a certain phase of my cycle, in the morning, with or without food or whether to put the drops under my tongue or in a drink. I opted for doing two under my tongue, in the morning on an empty stomach. I started taking the product on the first day of my period which is usually light and lasts 3 days. Well this product made my period basically non-existent, it made me very irritable and less energetic during a part of my cycle when I am usually happy and full of energy, when my PMS is over. I stopped taking the product after about four or five days and the next morning I was bright and happy, with no irritation. I also noticed that my skin got a big greasier as soon as I started taking the product and went back to normal right after I stopped. I am still going to try this product out during my luteal/ PMS phase of my cycle only because of the research I did and the great feedback pregnenolone has and hope that I will have better luck then. I wish the seller took a bit more effort to include a small pamphlet explaining the product, how and when to take it, possible side effects, and went to stop taking it. They should also explain that you can get your hormones tested to see whether you really need this product or not. Which is what I am going to do. I got this information by watching several YouTube videos. If I had not watched the YouTube videos and done my own research I would not have put two and two together and known that the pregnenolone was causing my irritation. Maybe I should have looked for a pregnenolone sellers that are also interested in educating and informing their clients and not just selling their product, then only reaching out to them asking they write a good review so they can fatten their pockets.
B**7
Works fast improving sleep and memory!
With age and other health issues my body has not been able to produce the nec. amount of hormones. This droplet form Pregnenolone by BioMatrix has helped balance my hormones (my functional doctor has seen my markers improve). I see an improvement with my memory and sleep. I love that it is in droplet form and goes straight into the blood stream.
S**L
This product has changed my life.
I suffer from anxiety. It causes extra hair loss, lack of sleep, acting irrational to situations and lack of focus, etc. I started taking the product to help with my anxiety. The first night I used it I noticed a big difference in my sleep. I slept so much better. I only use 2 drops before bed. As time went on I started noticing my hair growing back and not falling out as much, my sleep has gotten 90% better, my focus is better, situations that normally trigger my anxiety don't affect me as much. I recommend this product. I also have Hashimotos. I do believe this product is helping to regulate my hormones. My monthly cycle has been so much better. I will suggest putting 2 drops on a clean plate and licking it off or drop 2 drops on your hand and lick it off. I know it sounds weird but the drops are so small and you can't monitor how many drops you actually put in your mouth without standing in front of a mirror. Also it tastes like mint. I give 5 stars for the life saving product.
J**D
This thing is powerful!
I believe this product has worked for me because after using it a couple of days I feel so much better. I'm happier and I'm sleeping much better. The only change I've made is to include this product in my routine.
S**.
Wouldn’t live without it anymore!!
Have been taking for 3 months now and feel better than ever!!! I'm 42 and was struggling with bad PMS and anxiety. I would have a few nice days after my period and be in a good mood and then I would start getting anxious again about what’s to come. Absolutely crazy! This product really changed everything!! Apparently it doesn’t work for everyone but I won’t go without it again! It totally balanced me out and I feel like myself again. Any peri menopausal symptoms have vanished. I still wake up most nights but no sweating or panic. I take it,like someone suggested in the reviews here. 4 drops before bed,licked from my palm. Worth every penny!!
C**S
DOES Work - Do your condition homework 1st / find a good Doctor
Do hormone/symptoms homework 1st before buying. Find the right dose for your condition. There are many conditions this treats not just hormonal. Read Dr John Lee and Ray Sahelian Books. Best advise is seek a good Doctor. This does work. Biomatrix company take a look. Age does matter. Suitable for middle to older men and women. Best second hand book for dosing is Pregnenolone nature's feel good hormone by Ray Sahelian M.D. **BUT REMEMBER we are all individuals !** Best taken in the morning, lick drops off a saucer then leave on tongue and lay down on bed for 10 mins so this gets into body systems. Can be used in combination of other Bioidentical hormones because as you get older your private parts loose their hormone making ability e.g so taking this if your periods have completely stopped, may be an unreliable source on its own. Depends on what you are using this for. It may be better on its own/ or combination of hormones. Been used for many conditions see Ray's book PMS, Prostrate cancer, Arthritis and Stress etc. Find a Doctor to test and dose for your condition. If you can.
M**.
Unsure of benefits yet
Opened the bottle and couldn’t get over the potent smell, I couldn’t bring myself to taste it, so got my husband too. He said it was fine, not sure of the benefits, as haven’t started taking it myself. There is little, ‘how to take’ instructions but you can google it.
V**A
Pleasant tasting hopefully works!
Hope it is working to help with menopause anxiety and insomnia. I lick 2 drops off a saucer as recommended in another post - easiest way to ensure correct dose. Pleasant tasting.
E**A
Bad value
Very expensive for what you get. The manufacturer recommends 2x2 drops per day but studies show that 100mg per week is a good starting dose. You would get a superior product (in powder form) from health natura. No affiliation. I just couldn't wait for the shipment to arrive from the US.
Trustpilot
2 months ago
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